Zdravotn\u00edcke laborantky: <\/strong><\/p>\n\n\n\nIveta \u010euricov\u00e1
Gabriela Pauliakov\u00e1
Andrea \u0160kult\u00e9tyov\u00e1<\/p>\n\n\n\n
Sanit\u00e1rky: <\/strong>
Zdena Danieli\u010dov\u00e1
Zuzana Pl\u0161kov\u00e1<\/p>\n\n\n\nLaborat\u00f3rium: <\/strong>tel. 048 \u2013 2820 441, 338
Denn\u00e1 miestnos\u0165<\/strong>: tel. 048 \u2013 2820 339<\/p>\n\n\n\nPracovisko klinickej mikrobiol\u00f3gie NsP Brezno, n.o. je moderne vybaven\u00e9 laborat\u00f3rne diagnostick\u00e9 pracovisko. Zabezpe\u010duje komplexn\u00fa laborat\u00f3rnu diagnostiku ochoren\u00ed mikrobi\u00e1lnej etiol\u00f3gie pre ambulantn\u00fdch a hospitalizovan\u00fdch pacientov \u0161t\u00e1tnych i ne\u0161t\u00e1tnych zdravotn\u00edckych zariaden\u00ed. Zaober\u00e1 sa diagnostikou ochoren\u00ed sp\u00f4soben\u00fdch patog\u00e9nnymi aer\u00f3bnymi a anaer\u00f3bnymi bakt\u00e9riami, v\u00edrusmi, mikromyc\u00e9tami a parazitmi<\/strong>. Vykon\u00e1va priame (mikroskopick\u00e9, kultiva\u010dn\u00e9 vy\u0161etrenia, d\u00f4kaz antig\u00e9nov,molekul\u00e1rne met\u00f3dy) a nepriame diagnostick\u00e9 met\u00f3dy (d\u00f4kaz tvorby protil\u00e1tok).
V\u00fdznam mikrobiologickej diagnostiky v s\u00fa\u010dasnosti naber\u00e1 ve\u013ek\u00fd v\u00fdznam. Vzh\u013eadom k neust\u00e1le narastaj\u00facej rezistencii,<\/strong> citlivos\u0165 patog\u00e9nov na antibiotik\u00e1 a antimykotik\u00e1 dnes u\u017e nie je mo\u017en\u00e9 odhadn\u00fa\u0165<\/strong>.
Pod\u013ea z\u00e1kladn\u00fdch princ\u00edpov racion\u00e1lnej antibiotickej lie\u010dby, mus\u00ed predp\u00edsaniu empirickej (\u00favodnej) antibiotickej lie\u010dbe predch\u00e1dza\u0165 odber materi\u00e1lu na kultiva\u010dn\u00e9 vy\u0161etrenie<\/strong> (mo\u010dov\u00e9 infekcie, hnisav\u00e9 z\u00e1paly mandl\u00ed, z\u00e1paly p\u013e\u00fac, ucha, pr\u00ednosov\u00fdch dut\u00edn, ranov\u00e9 infekcie a pod.). Po 2-3 d\u0148och je potrebn\u00e9 vykona\u0165 rev\u00edziu \u2013 op\u00e4tovn\u00e9 zhodnotenie klinick\u00e9ho stavu pacienta, laborat\u00f3rnych a mikrobiologick\u00fdch v\u00fdsledkov a prehodnoti\u0165 doteraj\u0161iu antibiotick\u00fa lie\u010dbu.<\/p>\n\n\n\nS\u00fa\u010das\u0165ou mikrobiologick\u00fdch vy\u0161etren\u00ed je:<\/h3>\n\n\n\n\n- ur\u010denie citlivosti izolovan\u00fdch patog\u00e9nov na antibiotik\u00e1 a\u00a0antimykotik\u00e1 <\/strong>\u2013 kvalitat\u00edvne (diskov\u00fd test) a kvantitat\u00edvne vy\u0161etrenie citlivosti (MIC \u2013 minim\u00e1lna inhibi\u010dn\u00e1 koncentr\u00e1cia) na be\u017en\u00e9 aj rezervn\u00e9 antibiotik\u00e1, vr\u00e1tane ur\u010denia farmakodynamick\u00fdch parametrov antibiot\u00edk a\u00a0n\u00e1vrhu individualizovan\u00e9ho d\u00e1vkovania pre pacienta,<\/li>\n\n\n\n
- ur\u010denie mechanizmov rezistencie \u2013 <\/strong>d\u00f4le\u017eit\u00e1 inform\u00e1cia z\u00a0h\u013eadiska interpret\u00e1cie v\u00fdsledkov citlivosti na antibiotik\u00e1 a\u00a0aj z\u00a0epidemiologick\u00fdch d\u00f4vodov (identifik\u00e1cia epidemiologicky nebezpe\u010dn\u00fdch kme\u0148ov vy\u017eaduj\u00facich protiepidemick\u00e9 opatrenia),<\/li>\n\n\n\n
- interpret\u00e1cia v\u00fdsledkov \u2013 <\/strong>odl\u00ed\u0161enie potenci\u00e1lnych patog\u00e9nov od be\u017enej mikrofl\u00f3ry, odl\u00ed\u0161enie koloniz\u00e1cie, kontamin\u00e1cie a\u00a0infekcie, n\u00e1vrh antibiotickej lie\u010dby, interpret\u00e1cia v\u00fdsledkov s\u00e9rologick\u00fdch vy\u0161etren\u00ed a\u00a0pod.<\/li>\n<\/ul>\n\n\n\n
Be\u017en\u00e9 kultiva\u010dn\u00e9 vy\u0161etrenie<\/strong> biologick\u00e9ho materi\u00e1lu trv\u00e1 24 \u2013 72 hod\u00edn<\/strong>. V\u010faka vyspelej technike a zavedeniu modern\u00fdch vy\u0161etrovac\u00edch postupov vieme poskytn\u00fa\u0165 v\u00fdsledky mnoh\u00fdch vy\u0161etren\u00ed u\u017e do 2 hod\u00edn<\/strong> od doru\u010denia do laborat\u00f3ria<\/strong> \u2013 molekul\u00e1rna diagnostika a<\/strong> antig\u00e9ny <\/strong>v r\u00f4znych biologick\u00fdch materi\u00e1loch (Clostridium difficile, Streptococcus pneumoniae, Campylobacter spp., Salmonella spp., Shigella spp., Yersinia enterocolica, Listeria monocytogenes, Legionella pneumophila, Helicobacter pylori, Chlamydia trachomatis<\/em>, SARS-CoV-2, chr\u00edpka A a B, adenov\u00edrusy, RSV, rotav\u00edrusy, norov\u00edrusy, astrov\u00edrusy dermatotropn\u00e9 a neurotropn\u00e9 v\u00edrusy (HSV typ 1 a 2, VZV, enterov\u00edrusy), Giardia lamblia, Cryptosporidium parvum<\/em> a i.). V\u00fdsledky mnoh\u00fdch protil\u00e1tok poskytujeme do 2 hod\u00edn<\/strong> (HBsAg a cel\u00fd panel markerov v\u00edrusovej hepatit\u00eddy typu B, anti-HIV, anti-HCV, anti-HAV IgM a IgG, anti-Leptospira<\/em> a i.). Zaveden\u00edm tzv. monotestov na stanovenie protil\u00e1tok, nie je potrebn\u00e9 \u010daka\u0165 na nazbieranie diagnostick\u00e9ho setu a vy\u0161etrenia poskytuje sk\u00f4r, spravidla do 5-24 hod\u00edn<\/strong> (Toxoplasma gondii<\/em>, EBV, CMV, HSV, VZV, Rubeola a i.). Spektrum pon\u00fakan\u00fdch vy\u0161etren\u00ed neust\u00e1le prisp\u00f4sobujeme aktu\u00e1lnym po\u017eiadavk\u00e1m a v\u00fdvoju na trhu.<\/p>\n\n\n\nKvalita diagnostickej \u010dinnosti je systematicky overovan\u00e1 intern\u00fdm a extern\u00fdm n\u00e1rodn\u00fdm aj medzin\u00e1rodn\u00fdm syst\u00e9mom kvality<\/em><\/strong> (EHK) a pravidelne z\u00edskavame certifik\u00e1ty od pr\u00edslu\u0161n\u00fdch organiz\u00e1ci\u00ed:<\/p>\n\n\n\n\n- N\u00e1rodn\u00e9 referen\u010dn\u00e9 centrum pre sledovanie rezistencie mikroorganizmov na antibiotik\u00e1 \u00daVZ SR v\u00a0Bratislave,<\/li>\n\n\n\n
- N\u00e1rodn\u00e9 referen\u010dn\u00e9 centrum pre salmonel\u00f3zy UVZ SR v Bratislave,<\/li>\n\n\n\n
- St\u00e1tn\u00ed zdravotn\u00ed \u00fastav, AP OML v Prahe.<\/li>\n<\/ul>\n\n\n\n
Klinick\u00fd mikrobiol\u00f3g pln\u00ed aj \u010fal\u0161ie d\u00f4le\u017eit\u00e9 \u00falohy v r\u00e1mci NsP Brezno, n.o.:<\/strong><\/p>\n\n\n\n\n- Pravidelne, v ro\u010dnom intervale, aktualizuje preh\u013eady rezistencie na antibiotik\u00e1<\/strong> osobitne pre komunitn\u00e9 infekcie v\u00a0okrese Brezno a\u00a0pre jednotliv\u00e9 o\u0161etrovacie jednotky nemocnice \u2013 lok\u00e1lne preh\u013eady s\u00fa d\u00f4le\u017eit\u00fdm podkladom pre indikovanie empirickej antibiotickej lie\u010dby, od celkov\u00fdch sa m\u00f4\u017eu podstatne l\u00ed\u0161i\u0165!<\/li>\n\n\n\n
- Pravidelne sa z\u00fa\u010dast\u0148uje na vizit\u00e1ch<\/strong> vybran\u00fdch l\u00f4\u017ekov\u00fdch oddelen\u00ed.<\/li>\n\n\n\n
- Poskytuje odborn\u00e9 konzult\u00e1cie<\/strong> a\u00a0konzili\u00e1rne vy\u0161etrenia<\/strong> s\u00a0odpor\u00fa\u010dan\u00edm antimikrobi\u00e1lnej lie\u010dby pod\u013ea klinickej diagn\u00f3zy a aktu\u00e1lnych laborat\u00f3rnych v\u00fdsledkov. Ako podklad pre n\u00e1vrh terapie sl\u00fa\u017eia aktu\u00e1lne mikrobiologick\u00e9 a\u00a0in\u00e9 laborat\u00f3rne vy\u0161etrenia a\u00a0preh\u013eady rezistencie na antibiotik\u00e1 dan\u00e9ho regi\u00f3nu, nemocnice a\u00a0oddelenia. Zoh\u013ead\u0148uje sa aj dostupnos\u0165 antiinfek\u010dn\u00fdch lie\u010div.<\/li>\n\n\n\n
- Schva\u013euje pou\u017eitie rezervn\u00fdch antibiot\u00edk<\/strong> v\u00a0lie\u010dbe kritick\u00fdch infekci\u00ed a\u00a0infekci\u00ed vyvolan\u00fdch multirezistentn\u00fdmi patog\u00e9nmi.<\/li>\n\n\n\n
- Navrhuje adekv\u00e1tnu d\u00e1vkovaciu sch\u00e9mu antibiot\u00edk a\u00a0antimykot\u00edk u\u00a0konkr\u00e9tneho pacienta.<\/strong><\/li>\n\n\n\n
- Usmer\u0148uje terapeutick\u00fd monitoring<\/strong> vybran\u00fdch antibiot\u00edk.<\/li>\n\n\n\n
- Zabezpe\u010duje vzdel\u00e1vanie<\/strong> zdravotn\u00edckeho person\u00e1lu v\u00a0problematike racion\u00e1lnej antiinfek\u010dnej lie\u010dby a\u00a0prevencie v\u00fdskytu multirezistentn\u00fdch nozokomi\u00e1lnych kme\u0148ov (akt\u00edvna \u00fa\u010das\u0165 sa celoslovensk\u00fdch, krajsk\u00fdch a region\u00e1lnych konferenci\u00e1ch a\u00a0semin\u00e1roch).<\/li>\n<\/ul>\n\n\n\n
Klinick\u00fd mikrobiol\u00f3g riadi a koordinuje pr\u00e1cu Komisie pre racion\u00e1lnu farmakoterapiu, antiinfek\u010dn\u00fa lie\u010dbu a liekov\u00fa politiku<\/em><\/strong> a Komisie pre sledovanie a anal\u00fdzu nozokomi\u00e1lnych n\u00e1kaz<\/em><\/strong>. Komisie s\u00fa poradn\u00fdm org\u00e1nom riadite\u013ea NsP Brezno, n.o. a pripravuj\u00fa :<\/p>\n\n\n\n\n- odborn\u00e9 usmernenia a\u00a0metodick\u00e9 pokyny k\u00a0racion\u00e1lnej antibiotickej lie\u010dbe a\u00a0prevencii nozokomi\u00e1lnych n\u00e1kaz,<\/li>\n\n\n\n
- guidelines empirickej lie\u010dby komunitn\u00fdch a\u00a0nozokomi\u00e1lnych infekci\u00ed a\u00a0chirurgickej profylaxie,<\/li>\n\n\n\n
- monitoruj\u00fa a\u00a0analyzuj\u00fa rezistenciu na antibiotik\u00e1,\u00a0spotrebu antiinfek\u010dn\u00fdch liekov a\u00a0v\u00fdskyt nozokomi\u00e1lnych n\u00e1kaz, v\u00a0pr\u00edpade potreby navrhuj\u00fa opatrenia.<\/li>\n<\/ul>\n\n\n\n
Zoznam pon\u00fakan\u00fdch vy\u0161etren\u00ed:<\/strong><\/h3>\n\n\n\nBAKTERIOL\u00d3GIA<\/strong><\/h4>\n\n\n\n\n- kultiva\u010dn\u00e9 vy\u0161etrenie v\u00fdterov z horn\u00fdch ciest d\u00fdchac\u00edch (z tonz\u00edl, nosa, nosohltanu),<\/li>\n\n\n\n
- kultiva\u010dn\u00e9 vy\u0161etrenie v\u00fdterov spojivkov\u00e9ho vaku<\/li>\n\n\n\n
- kultiva\u010dn\u00e9 vy\u0161etrenie v\u00fdterov z ucha<\/li>\n\n\n\n
- kultiva\u010dn\u00e9 a mikroskopick\u00e9 vy\u0161etrenie sp\u00fata, bronchoalveol\u00e1rnej lav\u00e1\u017ee a\u00a0endotrache\u00e1lneho aspir\u00e1tu<\/li>\n\n\n\n
- kultiva\u010dn\u00e9, pr\u00edp. mikroskopick\u00e9 vy\u0161etrenie gynekologick\u00e9ho materi\u00e1lu \u2013 v\u00fdtery z uretry, po\u0161vy, cervixu, stery z placenty, plodov\u00e1 voda, lochie, Bartholinyho \u017e\u013eazy …<\/li>\n\n\n\n
- kultiva\u010dn\u00e9 vy\u0161etrenie mo\u010du na kvantitat\u00edvnu bakteri\u00fariu<\/li>\n\n\n\n
- kultiva\u010dn\u00e9 vy\u0161etrenie v\u00fdterov z kone\u010dn\u00edka u hna\u010dkov\u00fdch ochoren\u00ed, u kontaktov s hna\u010dkov\u00fdm ochoren\u00edm a u evidovan\u00fdch bacilonosi\u010dov<\/li>\n\n\n\n
- kultiva\u010dn\u00e9 a mikroskopick\u00e9 vy\u0161etrenie hnisu a in\u00e9ho tekut\u00e9ho materi\u00e1lu (z povrchov\u00fdch, h\u013abkov\u00fdch a opera\u010dn\u00fdch r\u00e1n, exsud\u00e1ty, punkt\u00e1ty, empy\u00e9my a in\u00e9) na aer\u00f3bnu aj anaer\u00f3bnu kultiv\u00e1ciu<\/li>\n\n\n\n
- kultiva\u010dn\u00e9 vy\u0161etrenie v\u00fdterov z povrchov\u00fdch ko\u017en\u00fdch defektov, vy\u0161etrenie kan\u00fdl, kat\u00e9trov a dr\u00e9nov<\/li>\n\n\n\n
- kultiva\u010dn\u00e9 a mikroskopick\u00e9 vy\u0161etrenie krvi u septick\u00fdch stavov, aer\u00f3bne aj anaer\u00f3bne<\/li>\n\n\n\n
- kultiva\u010dn\u00e9 a mikroskopick\u00e9 vy\u0161etrenie mozgomie\u0161neho moku, aer\u00f3bne aj anaer\u00f3bne<\/li>\n\n\n\n
- kultiva\u010dn\u00e9 vy\u0161etrenie vysokon\u00e1ro\u010dn\u00fdch mikroorganizmov \u2013 anaer\u00f3by, Gardnerella vaginalis<\/em>, Neisseria gonorrhoeae<\/em><\/li>\n\n\n\n
- okrem be\u017en\u00e9ho antibiotikogramu, pon\u00fakame roz\u0161\u00edrenie vy\u0161etrenia citlivosti o rezervn\u00e9 antibiotik\u00e1 v pr\u00edpade zistenia rezistencie izolovan\u00e9ho patog\u00e9na, alebo na po\u017eiadanie lek\u00e1ra<\/li>\n\n\n\n
- ur\u010denie citlivosti kme\u0148ov izolovan\u00fdch z biologick\u00e9ho materi\u00e1lu na antibiotik\u00e1 (ATB):\n
\n- kvalitat\u00edvne<\/em> \u2013 dif\u00faznou diskovou met\u00f3dou<\/li>\n\n\n\n
- kvantitat\u00edvne<\/em> \u2013 vy\u0161etrenie MIC (minim\u00e1lna inhibi\u010dn\u00e1 koncentr\u00e1cia) be\u017en\u00fdch a rezervn\u00fdch antibiot\u00edk v pr\u00edpade rezistencie izolovan\u00fdch mikroorganizmov alebo na po\u017eiadanie lek\u00e1ra<\/li>\n<\/ul>\n<\/li>\n\n\n\n
- detekcia produkcie beta-laktam\u00e1z u vybran\u00fdch bakteri\u00e1lnych kme\u0148ov<\/li>\n\n\n\n
- skr\u00edning nosi\u010dstva CPE (karbapenem\u00e1zy produkuj\u00face enterobakt\u00e9rie) v\u00a0stolici \u2013 v\u0161etky v\u00fdtery u\u00a0hospitalizovan\u00fdch pacientov, u\u00a0pacientov ambulantn\u00fdch len na po\u017eiadanie<\/li>\n\n\n\n
- stanovenie antig\u00e9nov v\u00a0stolici \u2013 Clostridium difficile <\/em>(GDH, tox\u00edn A\u00a0a\u00a0B), , Campylobacter spp., Salmonella spp., Shigella spp., Yersinia enterocolica, Listeria monocytogenes, Helicobacter pylori <\/em>a\u00a0i.<\/li>\n\n\n\n
- d\u00f4kaz antig\u00e9nov v\u00a0mo\u010di \u2013 Streptococcus pneumoniae, Legionella pneumophila<\/em><\/li>\n\n\n\n
- d\u00f4kaz antig\u00e9nov v\u00a0stere z\u00a0uretry, cervixu, pr\u00edp. v\u00a0mo\u010di \u2013 Chlamydia trachomatis, Neisseria gonorrhoeae<\/em><\/li>\n<\/ul>\n\n\n\n
Molekul\u00e1rna diagnostika<\/strong><\/p>\n\n\n\n\n- d\u00f4kaz nukleov\u00fdch kysel\u00edn respira\u010dn\u00fdch v\u00edrusov met\u00f3dou multiplex RT-qPCR \u2013 v\u00edrus chr\u00edpky A\u00a0a\u00a0B, RSV, SARS-CoV-2<\/li>\n\n\n\n
- d\u00f4kaz nukleov\u00fdch kysel\u00edn neurotropn\u00fdch a dermatotropn\u00fdch v\u00edrusov met\u00f3dou multiplex RT-qPCR \u2013 HSV typ 1 a 2, VZV, enterov\u00edrus<\/li>\n\n\n\n
- v bud\u00facnosti pl\u00e1nujem spektrum poskytovan\u00fdch vy\u0161etren\u00ed \u010falej roz\u0161irova\u0165<\/li>\n<\/ul>\n\n\n\n
<\/strong>PARAZITOL\u00d3GIA<\/strong><\/h4>\n\n\n\n\n- mikroskopick\u00e9 vy\u0161etrenie stolice na pr\u00edtomnos\u0165 \u010drevn\u00fdch helmintov a protozo\u00ed<\/li>\n\n\n\n
- perian\u00e1lne zlepy na pr\u00edtomnos\u0165 vaj\u00ed\u010dok Enterobius vermicularis<\/em><\/li>\n\n\n\n
- kultiva\u010dn\u00e9 a mikroskopick\u00e9 vy\u0161etrenie gynekologick\u00e9ho materi\u00e1lu na pr\u00edtomnos\u0165 Trichomonas vaginalis<\/em> (materi\u00e1l odobrat\u00fd priamo do transportnej p\u00f4dy)<\/li>\n\n\n\n
- stanovenie antig\u00e9nov v\u00a0stolici \u2013 Giardia lamblia, Cryptosporidium parvum<\/em><\/li>\n<\/ul>\n\n\n\n
<\/strong>VIROL\u00d3GIA<\/strong><\/h4>\n\n\n\n\n- d\u00f4kaz antig\u00e9nov v\u00a0nazofarynge\u00e1lnom aspir\u00e1te (naj\u010dastej\u0161\u00ed p\u00f4vodcovia v\u00edrusov\u00fdch infekci\u00ed d\u00fdchac\u00edch ciest) \u2013 v\u00edrus chr\u00edpky typu A\u00a0a\u00a0typu B, RSV, respira\u010dn\u00fd adenov\u00edrus<\/li>\n\n\n\n
- d\u00f4kaz antig\u00e9nov v\u00a0stolici \u2013 naj\u010dastej\u0161\u00ed p\u00f4vodcovia v\u00edrusov\u00fdch hna\u010dkov\u00fdch ochoren\u00ed \u2013 norov\u00edrusy, rotav\u00edrusy, adenov\u00edrusy, astrov\u00edrusy a\u00a0d\u00f4kaz enterov\u00edrusov (ECHO, Coxsackie A, B a\u00a0i.; p\u00f4vodcovia infekci\u00ed d\u00fdchac\u00edch ciest, vyr\u00e1\u017ekovit\u00fdch ochoren\u00ed, hor\u00fa\u010dkovit\u00e9 ochorenia a\u00a0i. v\u017edy s\u00fa sprev\u00e1dzan\u00e9 pr\u00edtomnos\u0165ou enterov\u00edrusov v\u00a0stolici aj bez hna\u010dky)<\/li>\n<\/ul>\n\n\n\n
<\/strong>IMUNOS\u00c9ROLOGIA \u2013<\/strong> v s\u00e9re pacienta dokazuje pr\u00edtomnos\u0165 protil\u00e1tok vzniknut\u00fdch v d\u00f4sledku \u0161pecifickej imunity organizmu na vniknut\u00e9 agens. Zabezpe\u010duje laborat\u00f3rnu diagnostiku ochoren\u00ed vyvolan\u00fdch bakt\u00e9riami, v\u00edrusmi a parazitmi:<\/p>\n\n\n\n\n- EBV v\u00edrus (Epstein-Barrovej v\u00edrus) a infek\u010dn\u00e1 mononukle\u00f3za: IM-test (orienta\u010dn\u00fd test), anti-VCA-IgM, IgG, anti-EBNA IgG (ur\u010denie \u0161t\u00e1dia infekcie)<\/li>\n\n\n\n
- Cytomegalov\u00edru: anti-CMV IgM, IgG<\/li>\n\n\n\n
- Herpes simplex v\u00edrus typ 1, 2: anti-HSV, IgM, IgG<\/li>\n\n\n\n
- Herpes-zoster v\u00edrus: anti-VZV IgM, IgG<\/li>\n\n\n\n
- anti-SARS-CoV-2 IgM, IgG<\/li>\n\n\n\n
- Bordetella pertussis toxin IgA, IgG (NOV\u00c9!)<\/li>\n\n\n\n
- Klie\u0161\u0165ov\u00e1 encefalit\u00edda IgM, IgG (NOV\u00c9)<\/li>\n\n\n\n
- Rubeola: anti-rubeola IgM, IgG<\/li>\n\n\n\n
- syfilis: RRR (r\u00fdchla reag\u00ednov\u00e1 reakcia) a TPHA (Treponema pallidum<\/em> hemaglutina\u010dn\u00fd test), anti-Syphylis IgM, IgG<\/li>\n\n\n\n
- Toxoplazm\u00f3za: anti-Toxoplasma gondii<\/em> IgM, IgG<\/li>\n\n\n\n
- Boreli\u00f3za: anti-Borrelia burgdorferri<\/em> IgM, IgG<\/li>\n\n\n\n
- Chlamydia trachomatis<\/em>: IgA, IgG<\/li>\n\n\n\n
- Chlamydia pneumoniae<\/em>: IgM, IgA, IgG<\/li>\n\n\n\n
- Mycoplasma pneumoniae<\/em>: IgM, IgA, IgG<\/li>\n\n\n\n
- HIV: anti-HIV typ 1, 2<\/li>\n\n\n\n
- v\u00edrusov\u00e1 hepatit\u00edda typu A: anti-HAV IgM, IgG<\/li>\n\n\n\n
- v\u00edrusov\u00e1 hepatit\u00edda typu B: HBsAg, anti-HBs<\/li>\n\n\n\n
- v\u00edrusov\u00e1 hepatit\u00edda typu C : anti-HCV<\/li>\n\n\n\n
- Leptospira<\/em>: anti-Leptospira<\/em> IgM, IgG<\/li>\n\n\n\n
- Mycobacterium tuberculosis<\/em>: anti-TBC IgM, IgG<\/li>\n<\/ul>\n\n\n\n
Odpor\u00fa\u010dan\u00e9 odberov\u00e9 s\u00fapravy:<\/strong><\/h3>\n\n\n\n\n- Bakteriol\u00f3gia<\/strong>:<\/li>\n\n\n\n
- steriln\u00fd tamp\u00f3n v transportnej p\u00f4de<\/li>\n\n\n\n
- uzavret\u00e1 steriln\u00e1 sk\u00famavka, steriln\u00e1 strieka\u010dka na odber tekut\u00e9ho materi\u00e1lu<\/li>\n\n\n\n
- steriln\u00e1 n\u00e1doba na odber sp\u00fata<\/li>\n\n\n\n
- hemokultiva\u010dn\u00e9 odberov\u00e9 n\u00e1doby (BACTEC) \u2013 Plus Aerobic\/F (aer\u00f3bna kultiv\u00e1cia, obsahuje absorbenty antibiot\u00edk), Plus Anaerobic\/F (anaer\u00f3bna kultiv\u00e1cia), PEDS Plus\/F (pre pediatrick\u00fdch pacientov)<\/li>\n\n\n\n
Molekul\u00e1rna diagnostika: <\/strong>odberov\u00e1 s\u00faprava s\u00a0transportn\u00fdm viruc\u00eddnym m\u00e9diom ur\u010den\u00e1 na molekul\u00e1rnu diagnostiku<\/p>
<\/li>\n\n\n\n- Imunos\u00e9rologia<\/strong>: sk\u00famavky pre odber krvi (pod\u013ea po\u010dtu po\u017eadovan\u00fdch vy\u0161etren\u00ed prisp\u00f4sobi\u0165 mno\u017estvo odobratej krvi (5-10ml)<\/li>\n\n\n\n
- Parazitol\u00f3gia: <\/strong>uzavret\u00e9 n\u00e1doby (nemusia by\u0165 steriln\u00e9) a skl\u00ed\u010dka s lepiacou p\u00e1skou <\/strong><\/li>\n<\/ul>\n\n\n\n
![\"\"](\"https:\/\/nspbr.sk\/web\/wp-content\/uploads\/2019\/03\/IMG_20190322_102321-1024x768.jpg\")
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<\/figure>\n","protected":false},"excerpt":{"rendered":"OKL – pracovisko klinickej mikrobiol\u00f3gie Ved\u00faci pracovn\u00edk pre SVaLZ:\u00a0MUDr. Zuzana K\u00f3nyov\u00e1, PhD.Telef\u00f3n:048\/ 2820 441 laborat\u00f3rium Pracovn\u00e1 doba: \u00a0Pondelok \u2013 Sobota: 7:00 \u2013 15:00po\u010das sviatkov poskytneme inform\u00e1ciu o\u00a0pracovnej dobe na po\u017eiadanie Samostatn\u00fd \u010dl\u00e1nok o oddelen\u00ed bol zverejnen\u00fd tu. Dokumenty na stiahnutie: U\u017eito\u010dn\u00e9 odkazy: Odborn\u00fd z\u00e1stupca: MUDr. Zuzana K\u00f3nyov\u00e1, PhD.atest\u00e1cia: klinick\u00e1 mikrobiol\u00f3gia\u010d.t.: 048 \u2013 2820 449e-mail: […]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":39,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_monsterinsights_skip_tracking":false,"footnotes":""},"class_list":["post-45","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/www.nspbr.sk\/web\/wp-json\/wp\/v2\/pages\/45","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.nspbr.sk\/web\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www.nspbr.sk\/web\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www.nspbr.sk\/web\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.nspbr.sk\/web\/wp-json\/wp\/v2\/comments?post=45"}],"version-history":[{"count":5,"href":"https:\/\/www.nspbr.sk\/web\/wp-json\/wp\/v2\/pages\/45\/revisions"}],"predecessor-version":[{"id":9185,"href":"https:\/\/www.nspbr.sk\/web\/wp-json\/wp\/v2\/pages\/45\/revisions\/9185"}],"up":[{"embeddable":true,"href":"https:\/\/www.nspbr.sk\/web\/wp-json\/wp\/v2\/pages\/39"}],"wp:attachment":[{"href":"https:\/\/www.nspbr.sk\/web\/wp-json\/wp\/v2\/media?parent=45"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}